person in the world to be cured of HIV using a new therapy designed by
a team of scientists from five United Kingdom universities.
50 people to complete a trial of the ambitious treatment, designed by
scientists and doctors from five of Britain’s leading universities.
Institute for Health Research Office for Clinical Research
Infrastructure, UK, Mark Samuels, said the treatment was the first
therapy created to have tracked down and destroyed HIV in every part of
the body, including in the dormant cells that evade current treatments.
of London that presently “the virus is completely undetectable in the
man’s blood, although that could be as a result of regular drugs.”
serious attempts at a full cure for HIV. We are exploring the real
possibility of curing HIV. This is a huge challenge and it’s still early
days but the progress has been remarkable.”
researchers from the universities of Oxford, Cambridge, Imperial
College, London, University College, London and King’s College, London.
targets the immune system, splicing itself into the DNA of T-cells so
that they not only ignore the disease, but turn into viral factories
which reproduce the virus.
Firstly, a vaccine helps the body to recognise the HIV-infected cells so
it can clear them out. Secondly, a new drug called Vorinostat activates
the dormant T-cells so they can be spotted by the immune system.
College, London, Prof. Sarah Fidler, said the new therapy was
specifically designed to clear the body of all HIV viruses, including
laboratory and there is good evidence it will work in humans too, but we
must stress we are still a long way from any actual therapy.
the next five years and at the moment we are not recommending stopping
ART but in the future, depending on the test results, we may explore
HIV. He is Timothy Brown, also known as the ‘second’ Berlin patient, who
received a stem cell transplant from a patient with natural immunity to
HIV in 2008.